C21ORF45 anticorps (AA 1-233)

N° du produit ABIN7599127

Cet anticorps Lapin Polyclonal détecte spécifiquement C21ORF45 dans WB, ELISA, IF, FACS et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour C21ORF45 anticorps (AA 1-233) (ABIN7599127)

Antigène: C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C21ORF45 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-C21ORF45 anticorps

Épitope: AA 1-233

Fonction: Anti-C21orf45/MIS18A Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-C21orf45/MIS18A Antibody Picoband® (ABIN7599127). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human C21orf45/MIS18A recombinant protein (Position: M1-D233).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Fujita, Y., Hayashi, T., Kiyomitsu, T., Toyoda, Y., Kokubu, A., Obuse, C., Yanagida, M. Priming of centromere for CENP-A recruitment by human hMi18-alpha, hMis18-beta, and M18BP1. Dev. Cell 12: 17-30, 2007. 2. Gross, M. B. Personal Communication. Baltimore, Md. 9/28/2018. 3. Kim, I. S., Lee, M., Park, K. C., Jeon, Y., Park, J. H., Hwang, E. J., Jeon, T. I., Ko, S., Lee, H., Baek, S. H., Kim, K. I. Roles of Mis18-alpha in epigenetic regulation of centromeric chromatin and CENP-A loading. Molec. Cell 46: 260-273, 2012.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur C21ORF45

Antigène: C21ORF45 (MIS18A) (MIS18 Kinetochore Protein Homolog A (MIS18A))

Autre désignation: MIS18A

Sujet:

Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3

Tissue Specificity: Brain. Expression restricted to astrocytes.

Background: Protein Mis18-alpha is a protein that in humans is encoded by the MIS18A gene. C21orf45, also named as MIS18A, C21orf46 and FASP1, is required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis. C21orf45 has dimer (~52 kDa) and heterodimer(~105 kDa) forms.

Poids moléculaire: 26 kDa

ID gène: 54069