PSMA5 anticorps (AA 1-241)

N° du produit ABIN7599141

Cet anticorps anti-PSMA5 est un anticorps Lapin Polyclonal détectant PSMA5 dans WB, ELISA, IF, ICC et FACS. Adapté pour Humain, Souris, Rat et Singe.

Aperçu rapide pour PSMA5 anticorps (AA 1-241) (ABIN7599141)

Antigène: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA5 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-PSMA5 anticorps

Épitope: AA 1-241

Fonction: Anti-PSMA5 Antibody Picoband®

Attributs du produit: Anti-PSMA5 Antibody Picoband® (ABIN7599141). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PSMA5 recombinant protein (Position: M1-I241). Human PSMA5 shares 100% and 98.8% amino acid (aa) sequence identity with mouse and rat PSMA5, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Coux, O., Tanaka, K., Goldberg, A. L. Structure and functions of the 20S and 26S proteasomes. Ann. Rev. Biochem. 65: 801-847, 1996. 2. DeMartino, G. N., Orth, K., McCullough, M. L., Lee, L. W., Munn, T. Z., Moomaw, C. R., Dawson, P. A., Slaughter, C. A. The primary structures of four subunits of the human, high molecular weight proteinase, macropain (proteasome), are distinct but homologous. Biochim. Biophys. Acta 1079: 29-38, 1991. 3. Mayau, V., Baron, B., Buttin, G., Debatisse, M. Twelve genes, including the unassigned proteasome zeta subunit gene, ordered within the human 1p13 region. Mammalian Genome 9: 331-333, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PSMA5

Antigène: PSMA5 (Proteasome Subunit alpha 5 (PSMA5))

Autre désignation: PSMA5

Sujet: Proteasome subunit alpha type-5 also known as 20S proteasome subunit alpha-5 is a protein that in humans is encoded by the PSMA5 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.

Poids moléculaire: 26 kDa

ID gène: 5686

UniProt: P28066

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA