MIOX anticorps (AA 1-266)

N° du produit ABIN7599187

Cet anticorps Lapin Polyclonal détecte spécifiquement MIOX dans WB, ELISA, IHC et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour MIOX anticorps (AA 1-266) (ABIN7599187)

Antigène: MIOX (Myo-Inositol Oxygenase (MIOX))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIOX est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-MIOX anticorps

Épitope: AA 1-266

Fonction: Anti-MIOX Antibody Picoband®

Attributs du produit: Anti-MIOX Antibody Picoband® (ABIN7599187). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MIOX recombinant protein (Position: M1-K266). Human MIOX shares 89.8% and 90.5% amino acid (aa) sequence identity with mouse and rat MIOX, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunohistochemistry, 2-5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arner, R. J., Prabhu, K. S., Thompson, J. T., Hildenbrandt, G. R., Liken, A. D., Reddy, C. C. Myo-inositol oxygenase: molecular cloning and expression of a unique enzyme that oxidizes myo-inositol and D-chiro-inositol. Biochem. J. 360: 313-320, 2001. 2. Gross, M. B. Personal Communication. Baltimore, Md. 3/31/2016. 3. Yang, Q., Dixit, J. B., Wada, J., Tian, Y., Wallner, E. I., Srivastva, S. K., Kanwar, Y. S. Identification of a renal specific oxido-reductase in newborn diabetic mice. Proc. Nat. Acad. Sci. 97: 9896-9901, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur MIOX

Antigène: MIOX (Myo-Inositol Oxygenase (MIOX))

Autre désignation: MIOX

Sujet: Myo-inositol oxygenase (MIOX), also known as ALDRL6, is a renal-specific member of the Aldo-keto reductase family. It catalyzes the first committed step in the Myo-inositol metabolism pathway and is widely distributed in mammalian tissues. Human Myo-inositol oxygenase shares 91 % and 96 % sequence homology with mouse and pig Myo-inositol oxygenase homologs, respectively. Myo-inositol oxygenase is responsible for the oxidative cleavage of Myo-inositol (MI) and its epimer D-chiro inositol (DCI) to D-glucuronate. The dioxygen-dependent cleavage of the C1-C6 bond in Myo-inositol is accomplished through the utilization of the FeII/FeIII binuclear iron center of MIOX. Myo-inositol oxygenase has also been implicated in complications of diabetes, including diabetic nephropathy.

Poids moléculaire: 36 kDa

ID gène: 55586

Pathways: Inositol Metabolic Process