MESP1 anticorps (AA 1-268)

N° du produit ABIN7599189

Cet anticorps anti-MESP1 est un anticorps Lapin Polyclonal détectant MESP1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour MESP1 anticorps (AA 1-268) (ABIN7599189)

Antigène: MESP1 (Mesoderm Posterior 1 (MESP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MESP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MESP1 anticorps

Épitope: AA 1-268

Fonction: Anti-MESP1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-MESP1 Antibody Picoband® (ABIN7599189). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MESP1 recombinant protein (Position: M1-K268).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lescroart, F., Wang, X., Lin, X., Swedlund, B., Gargouri, S., Sanchez-Danes, A., Moignard, V., Dubois, C., Paulissen, C., Kinston, S., Gottgens, B., Blanpain, C. Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq. Science 359: 1177-181, 2018. 2. Saga, Y., Hata, N., Kobayashi, S., Magnuson, T., Seldin, M. F., Taketo, M. M. MesP1: a novel basic helix-loop-helix protein expressed in the nascent mesodermal cells during mouse gastrulation. Development 122: 2769-2778, 1996. 3. Whittock, N. V., Sparrow, D. B., Wouters, M. A., Sillence, D., Ellard, S., Dunwoodie, S. L., Turnpenny, P. D. Mutated MESP2 causes spondylocostal dysostosis in humans. Am. J. Hum. Genet. 74: 1249-1254, 2004.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur MESP1

Antigène: MESP1 (Mesoderm Posterior 1 (MESP1))

Autre désignation: MESP1

Sujet:

Synonyms: Mesoderm posterior protein 1, Class C basic helix-loop-helix protein 5, bHLHc5, MESP1, BHLHC5

Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .

Background: Mesoderm posterior 1 homolog (mouse) is a protein that in humans is encoded by the MESP1 gene. It is mapped to 15q26.1. MESP1 is a transcription factor that regulates cardiovascular progenitor specification.The MESP1 gene encodes a member of the basic helix-loop-helix (bHLH) family of transcriptional regulatory proteins that may play a role in the development of nascent mesoderm.

Poids moléculaire: 29 kDa

ID gène: 55897

Pathways: Regulation of Muscle Cell Differentiation