FOSB anticorps (AA 1-332)

N° du produit ABIN7599279

Cet anticorps anti-FOSB est un anticorps Lapin Polyclonal détectant FOSB dans ELISA, IHC, IF et ICC. Adapté pour Humain.

Aperçu rapide pour FOSB anticorps (AA 1-332) (ABIN7599279)

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOSB est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-FOSB anticorps

Épitope: AA 1-332

Fonction: Anti-Fos B/FOSB Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Fos B/FOSB Antibody Picoband® (ABIN7599279). Tested in ELISA, IF, IHC, ICC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FOSB recombinant protein (Position: M1-S332).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kelz, M. B., Chen, J., Carlezon, W. A., Jr., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., Tkatch, T., Baranauskas, G., Surmeier, D. J., Neve, R. L., Duman, R. S., Picciotto, M. R., Nestler, E. J.Expression of the transcription factor delta-FosB in the brain controls sensitivity to cocaine.Nature 401: 272-276, 1999. 2. Martin-Gallardo, A., McCombie, W. R., Gocayne, J. D., FitzGerald, M. G., Wallace, S., Lee, B. M. B., Lamerdin, J., Trapp, S., Kelley, J. M., Liu, L.-I., Dubnick, M., Johnston-Dow, L. A., Kerlavage, A. R., de Jong, P., Carrano, A., Fields, C., Venter, J. C.Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3.Nature Genet. 1: 34-39, 1992. 3. Nakabeppu, Y., Nathans, D.A naturally occurring truncated form of FosB that inhibits Fos/Jun transcriptional activity.Cell 64: 751-759, 1991.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur FOSB

Antigène: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Autre désignation: FOSB

Sujet:

Synonyms: Vitamin K-dependent protein S, PROS1, PROS

Tissue Specificity: Plasma.

Background: FOSB, FBJ murine osteosarcoma viral oncogene homolog B, is a protein that, in humans, is encoded by the FOSB gene. FOSB is a member of Fos gene family which consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. The FOSB gene is mapped to 19q13.32. Delta FOSB is a truncated splice variant of FOSB. Delta FosB has been implicated in the development of drug addiction and control of the reward system in the brain, and is linked to changes in a number of other gene products such as CREB and sirtuins. Delta FosB also regulates the commitment of mesenchymal precursor cells to the adipocyte or osteoblast lineage.

Poids moléculaire: 75 kDa

ID gène: 2354

UniProt: P53539