NANS anticorps (AA 1-341)
Aperçu rapide pour NANS anticorps (AA 1-341) (ABIN7599289)
Antigène
Voir toutes NANS AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-341
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Fonction
- Anti-NANS Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-NANS Antibody (ABIN7599289). Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human NANS recombinant protein (Position: M1-E341). Human NANS shares 96.2% amino acid (aa) sequence identity with mouse NANS.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- NANS (N-Acetylneuraminic Acid Synthase (NANS))
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Autre désignation
- NANS
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Sujet
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Synonyms: NANS, SAS, Sialic acid synthase, N-acetylneuraminate synthase, EC 2.5.1.56, N-acetylneuraminate-9-phosphate synthase, EC 2.5.1.57, N-acetylneuraminic acid phosphate synthase, N-acetylneuraminic acid synthase
Background: Sialic acid synthase is an enzyme that in humans is encoded by the NANS gene. This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively, however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
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Poids moléculaire
- 38 kDa
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ID gène
- 54187
Antigène
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