Septin 7 anticorps (AA 1-351)

N° du produit ABIN7599301

Cet anticorps Lapin Polyclonal détecte spécifiquement Septin 7 dans WB, IHC, ELISA, IF et FACS. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Septin 7 anticorps (AA 1-351) (ABIN7599301)

Antigène: Septin 7 (SEPT7)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Septin 7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-Septin 7 anticorps

Épitope: AA 1-351

Fonction: Anti-SEPT7/SEPTIN7 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SEPT7/SEPTIN7 Antibody Picoband® (ABIN7599301). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SEPT7/SEPTIN7 recombinant protein (Position: M1-K351).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Kim, S. K., Shindo, A., Park, T. J., Oh, E. C., Ghosh, S., Gray, R. S., Lewis, R. A., Johnson, C. A., Attie-Bittach, T., Katsanis, N., Wallingford, J. B. Planar cell polarity acts through septins to control collective cell movement and ciliogenesis. Science 329: 1337-1340, 2010. 2. Kremer, B. E., Adang, L. A., Macara, I. G. Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell 130: 837-850, 2007. 3. Low, C., Macara, I. G. Structural analysis of septin 2, 6, and 7 complexes. J. Biol. Chem. 281: 30697-30706, 2006.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Septin 7

Antigène: Septin 7 (SEPT7)

Autre désignation: SEPTIN7

Sujet:

Synonyms: Lymphocyte antigen 6A-2/6E-1,Ly-6A.2/Ly-6E.1,Stem cell antigen 1,SCA-1,T-cell-activating protein,TAP,Ly6a,Ly6,

Tissue Specificity: Widely expressed. .

Background: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Poids moléculaire: 51 kDa

ID gène: 989

UniProt: Q16181