MafF anticorps (AA 1-37)

N° du produit ABIN7599317

L’anticorps Lapin Polyclonal anti-MafF a été validé pour ELISA, WB, IHC, FACS, ICC et IF. Il convient pour détecter MafF dans des échantillons de Humain.

Aperçu rapide pour MafF anticorps (AA 1-37) (ABIN7599317)

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MafF est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-MafF anticorps

Épitope: AA 1-37

Fonction: Anti-MAFF Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-MAFF Antibody Picoband® (ABIN7599317). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MAFF recombinant protein (Position: M1-L37).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dunham, I., Shimizu, N., Roe, B. A., Chissoe, S., Hunt, A. R., Collins, J. E., Bruskiewich, R., Beare, D. M., Clamp, M., Smink, L. J., Ainscough, R., Almeida, J. P., and 213 others. The DNA sequence of human chromosome 22. Nature 402: 489-495, 1999. Note: Erratum: Nature 404: 904 only, 2000. 2. Inoue, T., Kimura, T., Azuma, C., Inazawa, J., Takemura, M., Kikuchi, T., Kubota, Y., Ogita, K., Saji, F. Structural organization of the human oxytocin receptor gene. J. Biol. Chem. 269: 32451-32456, 1994. 3. Kimura, T., Ivell, R., Rust, W., Mizumoto, Y., Ogita, K., Kusui, C., Matsumura, Y., Azuma, C., Murata, Y. Molecular cloning of a human MafF homologue, which specifically binds to the oxytocin receptor gene in term myometrium. Biochem. Biophys. Res. Commun. 264: 86-92, 1999.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur MafF

Antigène: MafF (MAFF) (Transcription Factor MafF (MAFF))

Autre désignation: MAFF

Sujet:

Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27

Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Background: Transcription factor MafF is a bZip Maf transcription factor protein that in humans is encoded by the MAFF gene. The protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.

Poids moléculaire: 18 kDa

ID gène: 23764

Pathways: Myometrial Relaxation and Contraction