CBX8 anticorps (AA 1-389)

N° du produit ABIN7599340

Cet anticorps Souris Monoclonal détecte spécifiquement CBX8 dans WB, IHC et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour CBX8 anticorps (AA 1-389) (ABIN7599340)

Antigène: CBX8 (Chromobox Homolog 8 (CBX8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CBX8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 8G7

Détail du produit anti-CBX8 anticorps

Épitope: AA 1-389

Fonction: Anti-Cbx8 Antibody Picoband® (monoclonal, 8G7)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Cbx8 Antibody Picoband® (monoclonal, 8G7) (ABIN7599340). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Cbx8 recombinant protein (Position: M1-R389).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Bardos, J. I., Saurin, A. J., Tissot, C., Duprez, E., Freemont, P. S. HPC3 is a new human Polycomb orthologue that interacts and associates with RING1 and Bmi1 and has transcriptional repression properties. J. Biol. Chem. 275: 28785-28792, 2000. 2. Oza, J., Ganguly, B., Kulkarni, A., Ginjala, V., Yao, M., Ganesan, S. A novel role of chromodomain protein CBX8 in DNA damage response. J. Biol. Chem. 291: 22881-22893, 2016. Note: Erratum: J. Biol. Chem. 292: 761 only, 2017.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CBX8

Antigène: CBX8 (Chromobox Homolog 8 (CBX8))

Autre désignation: CBX8

Sujet:

Synonyms: 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2, PRKAB2

Tissue Specificity: Detected in fetal kidney, brain, liver and lung, and in adult brain and pancreas. Detected in hepatoma cell lines.

Background: CBX8 functions as a transcriptional repressor and has a role in DNA damage response. This gene is mapped to chromosome 17q25.3 based on an alignment of the CBX8 sequence with the genomic sequence (GRCh38).

Poids moléculaire: 45 kDa

ID gène: 57332