ELL anticorps (AA 1-407)

N° du produit ABIN7599363

Cet anticorps anti-ELL est un anticorps Lapin Polyclonal détectant ELL dans WB, ELISA, IF, ICC et FACS. Adapté pour Humain.

Aperçu rapide pour ELL anticorps (AA 1-407) (ABIN7599363)

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-ELL anticorps

Épitope: AA 1-407

Fonction: Anti-ELL Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ELL Antibody Picoband® (ABIN7599363). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ELL recombinant protein (Position: M1-S407).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Lavau, C., Luo, R. T., Du, C., Thirman, M. J. Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice. Proc. Nat. Acad. Sci. 97: 10984-10989, 2000. 2. Shilatifard, A., Lane, W. S., Jackson, K. W., Conaway, R. C., Conaway, J. W. An RNA polymerase II elongation factor encoded by the human ELL gene. Science 271: 1873-1876, 1996. 3. Thirman, M. J., Levitan, D. A., Kobayashi, H., Simon, M. C., Rowley, J. D. Cloning of ELL, a gene that fuses to MLL in a t(11,19)(q23,p13.1) in acute myeloid leukemia. Proc. Nat. Acad. Sci. 91: 12110-12114, 1994.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ELL

Antigène: ELL (Elongation Factor RNA Polymerase II (ELL))

Autre désignation: ELL

Sujet:

Synonyms: Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3, GSTM3, GST5,

Tissue Specificity: Testis and brain.

Background: RNA polymerase II elongation factor ELL is an enzyme that in humans is encoded by the ELL gene. Eleven-nineteen lysine-rich leukemia protein (ELL) was originally identified in a screen for genes that fuse to MLL (myeloid-lymphoid leukemia) in the t(11,19)(q23,p13.1) breakpoint. ELL is an elongation factor that increases the catalytic rate of RNA pol II by suppressing transient pausing of RNA pol II. ELL has been shown to be essential to development and important to cell growth and survival. Alternate names for ELL include RNA polymerase II elongation factor ELL, ELL1, and men.

Poids moléculaire: 60-80 kDa

ID gène: 8178

UniProt: P55199