MSL3 anticorps (AA 1-498)

N° du produit ABIN7599447

Cet anticorps anti-MSL3 est un anticorps Lapin Polyclonal détectant MSL3 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour MSL3 anticorps (AA 1-498) (ABIN7599447)

Antigène: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL3 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MSL3 anticorps

Épitope: AA 1-498

Fonction: Anti-MSL3 Antibody Picoband®

Attributs du produit: Anti-MSL3 Antibody Picoband® (ABIN7599447). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SLC7A7 recombinant protein (Position: M1-D498). Human SLC7A7 shares 90.8% and 91.6% amino acid (aa) sequence identity with mouse and rat SLC7A7, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Basilicata, M. F., Bruel, A.-L., Semplicio, G., Valsecchi, C. I. K., Aktas, T., Duffourd, Y., Rumpf, T., Morton, J., Bache, I., Szymanski, W. G., Gilissen, C., Vanakker, O., and 29 others. De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. Nature Genet. 50: 1442-1451, 2018. 2. Brunet, T., McWalter, K., Mayerhanser, K., Anbouba, G. M., Armstrong-Javors, A., Bader, I., Baugh, E., Begtrup, A., Bupp, C. P., Callewaert, B. L., Cereda, A., Cousin, M. A., and 49 others. Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. Genet. Med. 23: 384-395, 2021. 3. Prakash, S. K., Van den Veyver, I. B., Franco, B., Volta, M., Ballabio, A., Zoghbi, H. Y. Characterization of a novel chromo domain gene in Xp22.3 with homology to Drosophila msl-3. Genomics 59: 77-84, 1999.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur MSL3

Antigène: MSL3 (Male-Specific Lethal 3 Homolog (MSL3))

Autre désignation: MSL3

Sujet: Y+L amino acid transporter 1 is a protein that in humans is encoded by the SLC7A7 gene. The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.

Poids moléculaire: 70 kDa

ID gène: 10943

UniProt: Q8N5Y2