OCRL anticorps (AA 1-901)

N° du produit ABIN7599572

L’anticorps anti-OCRL Polyclonal Lapin est utilisé pour la détection de OCRL dans des échantillons de Humain. Il a été validé pour WB, ELISA, IHC, ICC et IF.

Aperçu rapide pour OCRL anticorps (AA 1-901) (ABIN7599572)

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OCRL est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-OCRL anticorps

Épitope: AA 1-901

Fonction: Anti-OCRL Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-OCRL Antibody (ABIN7599572). Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OCRL recombinant protein (Position: M1-D901).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur OCRL

Antigène: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Autre désignation: OCRL

Sujet:

Synonyms: G2/mitotic-specific cyclin-B2, CCNB2

Tissue Specificity: Strongly expressed in placenta. Expressed at lower levels in heart, pancreas, kidney and brain. Expressed in endothelial cells. Isoform alpha was found to be the predominant isoform. Isoform beta was not found in pancreas and brain.

Background: Inositol polyphosphate 5-phosphatase OCRL-1, also known as Lowe oculocerebrorenal syndrome protein, is an enzyme encoded by the OCRL gene located on the X chromosome in humans. This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Poids moléculaire: 104 kDa

ID gène: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process