DOCK1 anticorps (AA 100-1732)

N° du produit ABIN7599615

Cet anticorps anti-DOCK1 est un anticorps Lapin Polyclonal détectant DOCK1 dans ELISA, WB, IHC, IF et FACS. Adapté pour Humain.

Aperçu rapide pour DOCK1 anticorps (AA 100-1732) (ABIN7599615)

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-DOCK1 anticorps

Épitope: AA 100-1732

Fonction: Anti-DOCK180/DOCK1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-DO/DOCK1 Antibody Picoband® (ABIN7599615). Tested in ELISA, Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human DOCK180/DOCK1 recombinant protein (Position: S100-T1732).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Humann
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cote, J.-F., Vuori, K. Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J. Cell Sci. 115: 4901-4913, 2002. 2. Gross, M. B. Personal Communication. Baltimore, Md. 8/31/2016. 3. Hasegawa, H., Kiyokawa, E., Tanaka, S., Nagashima, K., Gotoh, N., Shibuya, M., Kurata, T., Matsuda, M. DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the membrane. Molec. Cell Biol. 16: 1770-176, 1996.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur DOCK1

Antigène: DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))

Autre désignation: DOCK1

Sujet:

Synonyms: Tumor necrosis factor-inducible gene 6 protein,Hyaluronate-binding protein,TNF-stimulated gene 6 protein,TSG-6,Tumor necrosis factor alpha-induced protein 6,TNF alpha-induced protein 6,TNFAIP6,TSG6,

Tissue Specificity: Found in the synovial fluid of patients with rheumatoid arthritis. .

Background: Dock180, (Dedicator of cytokinesis) also known as DOCK1, is a large (~180 kDa) protein involved in intracellular signalling networks. This gene encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. The encoded protein regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 215 kDa

ID gène: 1793

UniProt: Q14185

Pathways: Signaling of Hepatocyte Growth Factor Receptor