L’anticorps Lapin Polyclonal anti-LEPREL1 a été validé pour WB, ELISA, IHC, FACS, ICC et IF. Il convient pour détecter LEPREL1 dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN7599671
Aperçu rapide pour LEPREL1 anticorps (AA 106-494) (ABIN7599671)
Anti-P3H2 Antibody (ABIN7599671). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Purification
Immunogen affinity purified.
Immunogène
E.coli-derived human P3H2 recombinant protein (Position: E106-R494). Human P3H2 shares 88.9% and 89.5% amino acid (aa) sequence identity with mouse and rat P3H2, respectively.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Antigène
LEPREL1
(Leprecan Like Protein 1 (LEPREL1))
Autre désignation
P3H2
Sujet
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.