Tricellulin anticorps (AA 12-496)

N° du produit ABIN7599821

Cet anticorps Lapin Polyclonal détecte spécifiquement Tricellulin dans WB, IHC, ELISA et FACS. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Tricellulin anticorps (AA 12-496) (ABIN7599821)

Antigène: Tricellulin (MARVELD2)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tricellulin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Tricellulin anticorps

Épitope: AA 12-496

Fonction: Anti-MARVELD2 Antibody Picoband®

Attributs du produit: Anti-MARVELD2 Antibody Picoband® (ABIN7599821). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MARVELD2 recombinant protein (Position: R12-H496). Human MARVELD2 shares 87% amino acid (aa) sequence identity with mouse MARVELD2.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chishti, M. S., Bhatti, A., Tamim, S., Lee, K., McDonald, M.-L., Leal, S. M., Ahmad, W. Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families. J. Hum. Genet. 53: 101-105, 2008. 2. Ikenouchi, J., Furuse, M., Furuse, K., Sasaki, H., Tsukita, S., Tsukita, S. Tricellulin constitutes a novel barrier at tricellular contacts of epithelial cells. J. Cell Biol. 171: 939-945, 2005. 3. Riazuddin, S., Ahmed, Z. M., Fanning, A. S., Lagziel, A., Kitajiri, S., Ramzan, K., Khan, S. N., Chattaraj, P., Friedman, P. L., Anderson, J. M., Belyantseva, I. A., Forge, A., Riazuddin, S., Friedman, T. B. Tricellulin is a tight-junction protein necessary for hearing. Am. J. Hum. Genet. 79: 1040-1051, 2006.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Tricellulin

Antigène: Tricellulin (MARVELD2)

Autre désignation: MARVELD2

Sujet: MARVEL domain-containing protein 2 is a protein that in humans is encoded by the MARVELD2 gene. The protein encoded by this gene is a membrane protein found at the tight junctions between epithelial cells. The encoded protein helps establish epithelial barriers such as those in the organ of Corti, where these barriers are required for normal hearing. Defects in this gene are a cause of deafness autosomal recessive type 49 (DFNB49). Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 64 kDa

ID gène: 153562

UniProt: Q8N4S9

Pathways: Sensory Perception of Sound, Cell-Cell Junction Organization