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MMP28 anticorps (AA 123-505)

Cet anticorps anti-MMP28 est un anticorps Lapin Polyclonal détectant MMP28 dans WB, ELISA, IF, ICC et FACS. Adapté pour Humain.
N° du produit ABIN7599865

Aperçu rapide pour MMP28 anticorps (AA 123-505) (ABIN7599865)

Antigène

Voir toutes MMP28 Anticorps
MMP28 (Matrix Metallopeptidase 28 (MMP28))

Reactivité

  • 45
  • 12
  • 3
  • 2
  • 2
  • 2
  • 1
Humain

Hôte

  • 40
  • 5
Lapin

Clonalité

  • 42
  • 3
Polyclonal

Conjugué

  • 24
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MMP28 est non-conjugé

Application

  • 28
  • 18
  • 16
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Épitope

    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 123-505

    Fonction

    Anti-MMP28 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-MMP28 Antibody Picoband® (ABIN7599865). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human MMP28 recombinant protein (Position: F123-L505).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Illman, S. A., Keski-Oja, J., Lohi, J. Promoter characterization of the human and mouse epilysin (MMP-28) genes. Gene 275: 185-194, 2001. 2. Lohi, J., Wilson, C. L., Roby, J. D., Parks, W. C. Epilysin, a novel human matrix metalloproteinase (MMP-28) expressed in testis and keratinocytes and in response to injury. J. Biol. Chem. 276: 10134-10144, 2001. 3. Manicone, A. M., Birkland, T. P., Lin, M., Betsuyaku, T., van Rooijen, N., Lohi, J., Keski-Oja, J., Wang, Y., Skerrett, S. J., Parks, W. C. Epilysin (MMP-28) restrains early macrophage recruitment in Pseudomonas aeruginosa pneumonia. J. Immun. 182: 3866-3876, 2009.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    MMP28 (Matrix Metallopeptidase 28 (MMP28))

    Autre désignation

    MMP28

    Sujet

    Synonyms: Troponin I, fast skeletal muscle, Troponin I, fast-twitch isoform, TNNI2

    Tissue Specificity: Highly expressed in brain and weakly in heart, small intestine and uterus. Isoform 1A is mostly expressed in granular cell and molecular layer. Isoform 1B is mostly expressed in Purkinje cells. Isoform 1E is predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland. .

    Background: Matrix metalloproteinase 28 also known as epilysin is an enzyme that in humans is encoded by the MMP28 gene. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix for both normal physiological processes, such as embryonic development, reproduction and tissue remodeling, and disease processes, such as asthma and metastasis. This gene encodes a secreted enzyme that degrades casein. Its expression pattern suggests that it plays a role in tissue homeostasis and in wound repair. Alternative splicing of this gene results in multiple transcript variants.

    Poids moléculaire

    48 kDa

    ID gène

    79148

    UniProt

    Q9H239
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