P-Cadherin anticorps (AA 126-336)

N° du produit ABIN7599888

L’anticorps anti-P-Cadherin Monoclonal produit chez le Souris a été validé pour WB, IF et ICC. Il convient pour la détection de P-Cadherin dans des échantillons provenant de Humain. }

Aperçu rapide pour P-Cadherin anticorps (AA 126-336) (ABIN7599888)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp P-Cadherin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 3C9

Détail du produit anti-P-Cadherin anticorps

Épitope: AA 126-336

Fonction: Anti-P-Cadherin-3 CDH3-Antibody (monoclonal, 3C9)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-P-Cadherin-3 CDH3-Antibody (monoclonal, 3C9) (ABIN7599888). Tested in IF, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human P cadherin recombinant protein (Position: Q126-H336).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet:

Synonyms: Cadherin-3, Placental cadherin, P-cadherin, CDH3, CDHP

Tissue Specificity: Expressed in some normal epithelial tissues and in some carcinoma cell lines.

Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Poids moléculaire: 120 kDa

ID gène: 1001

UniProt: P22223