TYR anticorps (AA 130-529)

N° du produit ABIN7599956

Cet anticorps Lapin Polyclonal détecte spécifiquement TYR dans WB et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour TYR anticorps (AA 130-529) (ABIN7599956)

Antigène: TYR (Tyrosinase (TYR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYR est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TYR anticorps

Épitope: AA 130-529

Fonction: Anti-Tyrosinase/TYR Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Tyrosinase/TYR Antibody Picoband® (ABIN7599956). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Tyrosinase/TYR recombinant protein (Position: E130-K529).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bard, L. A. Heterogeneity in Waardenburg's syndrome: report of a family with ocular albinism. Arch. Ophthal. 96: 1193-1198, 1978. 2. Barton, D. E., Kwon, B. S., Francke, U. Human tyrosinase gene, mapped to chromosome 11 (q14-q21), defines second region of homology with mouse chromosome 7. Genomics 3: 17-24, 1988. 3. Berson, J. F., Frank, D. W., Calvo, P. A., Bieler, B. M., Marks, M. S. A common temperature-sensitive allelic form of human tyrosinase is retained in the endoplasmic reticulum at the nonpermissive temperature. J. Biol. Chem. 275: 12281-12289, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TYR

Antigène: TYR (Tyrosinase (TYR))

Autre désignation: TYR

Sujet:

Synonyms: Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1

Tissue Specificity: Highly expressed in heart and liver.

Background: The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene.

Poids moléculaire: 60-65 kDa

ID gène: 7299

UniProt: P14679