IL-10 anticorps (AA 137-178)

N° du produit ABIN7599986

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-10 dans IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour IL-10 anticorps (AA 137-178) (ABIN7599986)

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-10 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-IL-10 anticorps

Épitope: AA 137-178

Fonction: Anti-IL-10/IL10 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-IL-10/IL10 Antibody Picoband® (ABIN7599986). Tested in ELISA, IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IL-10/IL10 recombinant protein (Position: K137-N178).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL/mL, Human
ELISA, 0.1-0.5 μg/mL/mL, Human
1. Eskdale J, Kube D, Tesch H, Gallagher G (1997). "Mapping of the human IL10 gene and further characterization of the 5' flanking sequence".

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur IL-10

Antigène: IL-10 (IL10) (Interleukin 10 (IL10))

Autre désignation: IL10

Sujet:

Synonyms: Interleukin-10, IL-10, Cytokine synthesis inhibitory factor, CSIF, IL10

Tissue Specificity: Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

Background: Interleukin-10 (IL-10 or IL10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-γ, IL-2, IL-3, TNFα and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al. (1992) showed that the mouse Il 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al. (1997) mapped the IL10 gene to the junction between 1q31 and 1q32.

Poids moléculaire: 19 kDa

ID gène: 3586

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints