Neurogenin 3 anticorps (AA 137-214)

N° du produit ABIN7599987

L’anticorps Lapin Polyclonal anti-Neurogenin 3 a été validé pour WB, ELISA et FACS. Il convient pour détecter Neurogenin 3 dans des échantillons de Humain et Souris.

Aperçu rapide pour Neurogenin 3 anticorps (AA 137-214) (ABIN7599987)

Antigène: Neurogenin 3 (NEUROG3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Neurogenin 3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Neurogenin 3 anticorps

Épitope: AA 137-214

Fonction: Anti-NEUROG3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-NEUROG3 Antibody Picoband® (ABIN7599987). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NEUROG3 recombinant protein (Position: Q137-L214). Human NEUROG3 shares 72.2% amino acid (aa) sequence identity with mouse NEUROG3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Gradwohl, G., Dierich, A., LeMeur, M., Guillemot, F. Neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc. Nat. Acad. Sci. 97: 1607-1611, 2000. 2. Kim, S.-H., Warram, J. H., Krolewski, A. S., Doria, A. Mutation screening of the neurogenin-3 gene in autosomal dominant diabetes. J. Clin. Endocr. Metab. 86: 2320-2322, 2001. 3. Lee, C. S., Perreault, N., Brestelli, J. E., Kaestner, K. H. Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity. Genes Dev. 16: 1488-1497, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Neurogenin 3

Antigène: Neurogenin 3 (NEUROG3)

Autre désignation: NEUROG3

Sujet:

Synonyms: NEUROG3, ATOH5, BHLHA7, NGN3, Neurogenin-3, NGN-3, Class A basic helix-loop-helix protein 7, bHLHa7, Protein atonal homolog 5

Background: The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).

Poids moléculaire: 23 kDa

ID gène: 50674

UniProt: Q9Y4Z2