FGA anticorps (AA 139-784)

N° du produit ABIN7600004

Cet anticorps Lapin Polyclonal détecte spécifiquement FGA dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour FGA anticorps (AA 139-784) (ABIN7600004)

Antigène: FGA (Fibrinogen alpha Chain (FGA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGA est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-FGA anticorps

Épitope: AA 139-784

Fonction: Anti-Fibrinogen alpha chain/FGA Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Fibrinogen alpha chain/FGA Antibody Picoband® (ABIN7600004). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Fibrinogen alpha chain/FGA recombinant protein (Position: E139-Q784).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahn, H. J., Glickman, J. F., Poon, K. L., Zamolodchikov, D., Jno-Charles, O. C., Norris, E. H., Strickland, S. A novel A-beta-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease mice. J. Exp. Med. 211: 1049-1062, 2014. 2. Akassoglou, K., Yu, W.-M., Akpinar, P., Strickland, S. Fibrin inhibits peripheral nerve remyelination by regulating Schwann cell differentiation. Neuron 33: 861-875, 2002. 3. Alving, B. M., Henschen, A. H. Fibrinogen Giessen I: a congenital homozygously expressed dysfibrinogenemia with A-alpha arg-to-his substitution. Am. J. Hemat. 25: 479-482, 1987.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur FGA

Antigène: FGA (Fibrinogen alpha Chain (FGA))

Autre désignation: FGA

Sujet:

Synonyms: Fibrinogen alpha chain, FGA

Tissue Specificity: Detected in blood plasma (at protein level).

Background: Fibrinogen alpha chain?is a?protein?that in humans is encoded by the?FGA?gene. This gene encodes the alpha subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Following vascular injury, the encoded preproprotein is proteolytically processed by thrombin during the conversion of fibrinogen to fibrin. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia, afibrinogenemia and renal amyloidosis. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that undergoes proteolytic processing.

Poids moléculaire: 95 kDa

ID gène: 2243

UniProt: P02671