PRDM8 anticorps (AA 14-405)

N° du produit ABIN7600021

Cet anticorps anti-PRDM8 est un anticorps Lapin Polyclonal détectant PRDM8 dans WB, ELISA, ICC, IF et FACS. Adapté pour Humain.

Aperçu rapide pour PRDM8 anticorps (AA 14-405) (ABIN7600021)

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM8 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-PRDM8 anticorps

Épitope: AA 14-405

Fonction: Anti-PRDM8 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PRDM8 Antibody Picoband® (ABIN7600021). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRDM8 recombinant protein (Position: D14-D405).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Eom, G. H., Kim, K., Kim, S.-M., Kee, H. J., Kim, J.-Y., Jin, H. M., Kim, J.-R., Kim, J. H., Choe, N., Kim, K.-B., Lee, J., Kook, H., Kim, N., Seo, S.-B. Histone methyltransferase PRDM8 regulates mouse testis steroidogenesis. Biochem. Biophys. Res. Commun. 388: 131-136, 2009. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 11/11/2015. 3. Komai, T., Iwanari, H., Mochizuki, Y., Hamakubo, T., Shinkai, Y. Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr. Patterns 9: 503-514, 2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PRDM8

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Autre désignation: PRDM8

Sujet:

Synonyms: Interleukin-17B, IL-17B, Cytokine CX1, Cytokine-like protein ZCYTO7, Neuronal interleukin-17-related factor, Il17b, Nirf, Zcyto7

Tissue Specificity: Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Background: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 70 kDa

ID gène: 56978