PLS1 anticorps (AA 14-581)
Aperçu rapide pour PLS1 anticorps (AA 14-581) (ABIN7600032)
Antigène
Voir toutes PLS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 14-581
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Fonction
- Anti-PLS1 Antibody Picoband®
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Attributs du produit
- Anti-PLS1 Antibody Picoband® (ABIN7600032). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PLS1 recombinant protein (Position: E14-L581). Human PLS1 shares 93.8% amino acid (aa) sequence identity with mouse PLS1.
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Diaz-Horta, O., Bademci, G., Tokgoz-Yilmaz, S., Guo, S., Zafeer, F., Sineni, C. J., Duman, D., Farooq, A., Tekin, M. Novel variant pE269K confirms causative role of PLA1 mutations in autosomal dominant hearing loss. Clin. Genet. 96: 575-578, 2019. 2. Grimm-Gunter, E-M. S., Revenu, C., Ramos, S., Hurbain, I., Smyth, N., Ferrary, E., Louvard, D., Robine, S., Rivero, F. Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium. Molec. Biol. Cell 20: 2549-2562, 2009. 3. Lin, C.-S., Shen, W., Chen, Z. P., Tu, Y.-H., Matsudaira, P. Identification of I-plastin, a human fimbrin isoform expressed in intestine and kidney. Molec. Cell. Biol. 14: 2457-2467, 1994. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PLS1 (Plastin 1 (PLS1))
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Autre désignation
- PLS1
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Sujet
- Fimbrin also known as is plastin 1 is a protein that in humans is encoded by the PLS1 gene. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. The protein encoded by this gene is a third distinct plastin isoform, which is specifically expressed at high levels in the small intestine. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. A pseudogene of this gene is found on chromosome 11.
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Poids moléculaire
- 70 kDa
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ID gène
- 5357
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UniProt
- Q14651
Antigène
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