NCOA4 anticorps (AA 14-614)

N° du produit ABIN7600033

Cet anticorps anti-NCOA4 est un anticorps Lapin Polyclonal détectant NCOA4 dans WB, ELISA et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NCOA4 anticorps (AA 14-614) (ABIN7600033)

Antigène: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-NCOA4 anticorps

Épitope: AA 14-614

Fonction: Anti-NCOA4 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-NCOA4 Antibody Picoband® (ABIN7600033). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NCOA4 recombinant protein (Position: R14-M614).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. "Entrez Gene: NCOA4 Nuclear receptor coactivator 4". 2. Santoro M, Dathan NA, Berlingieri MT, Bongarzone I, Paulin C, Grieco M, Pierotti MA, Vecchio G, Fusco A (Feb 1994). "Molecular characterization of RET/PTC3, a novel rearranged version of the RETproto-oncogene in a human thyroid papillary carcinoma". Oncogene. 9 (2): 509-16. 3. Yeh S, Chang C (May 1996). "Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells". Proceedings of the National Academy of Sciences of the United States of America. 93 (11): 5517-21.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NCOA4

Antigène: NCOA4 (Nuclear Receptor Coactivator 4 (NCOA4))

Autre désignation: NCOA4

Sujet:

Synonyms: Urokinase-type plasminogen activator, U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B, PLAU

Tissue Specificity: Expressed in the prostate gland and prostate cancers.

Background: Nuclear receptor coactivator 4 is a protein that in humans is encoded by the NCOA4 gene. This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.

Poids moléculaire: 70 kDa

ID gène: 8031

UniProt: Q13772

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway