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MARS2 anticorps (AA 143-590)

Cet anticorps Lapin Polyclonal détecte spécifiquement MARS2 dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.
N° du produit ABIN7600058

Aperçu rapide pour MARS2 anticorps (AA 143-590) (ABIN7600058)

Antigène

Voir toutes MARS2 Anticorps
MARS2 (Methionyl-tRNA Synthetase 2, Mitochondrial (MARS2))

Reactivité

Humain, Rat, Souris

Hôte

  • 26
  • 3
Lapin

Clonalité

  • 28
  • 1
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MARS2 est non-conjugé

Application

  • 25
  • 13
  • 13
  • 10
  • 5
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • Épitope

    • 15
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 143-590

    Fonction

    Anti-MARS2 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-MARS2 Antibody Picoband® (ABIN7600058). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human MARS2 recombinant protein (Position: H143-A590).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Bayat, V., Thiffault, I., Jaiswal, M., Tetreault, M., Donti, T., Sasarman, F., Bernard, G., Demers-Lamarche, J., Dicaire, M.-J., Mathieu, J., Vanasse, M., Bouchard, J.-P., Rioux, M.-F., Lourenco, C. M., Li, Z., Haueter, C., Shoubridge, E. A., Graham, B. H., Brais, B., Bellen, H. J. Mutations in the mitochondrial methionyl-tRNA synthetase cause a neurodegenerative phenotype in flies and a recessive ataxia (ARSAL) in humans. PLos Biol. 10: e1001288, 2012. Note: Electronic Article. 2. Bonnefond, L., Fender, A., Rudinger-Thirion, J., Giege, R., Florentz, C., Sissler, M. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. Biochemistry 44: 4805-4816, 2005. 3. Gross, M. B. Personal Communication. Baltimore, Md. 1/28/2014.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    MARS2 (Methionyl-tRNA Synthetase 2, Mitochondrial (MARS2))

    Autre désignation

    MARS2

    Sujet

    Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3

    Tissue Specificity: Brain. Expression restricted to astrocytes.

    Background: This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3).

    Poids moléculaire

    70 kDa

    ID gène

    92935
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