TTLL3 anticorps (AA 144-762)

N° du produit ABIN7600063

Cet anticorps anti-TTLL3 est un anticorps Lapin Polyclonal détectant TTLL3 dans ELISA et WB. Adapté pour Humain.

Aperçu rapide pour TTLL3 anticorps (AA 144-762) (ABIN7600063)

Antigène: TTLL3 (Tubulin tyrosine Ligase-Like Family, Member 3 (TTLL3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TTLL3 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-TTLL3 anticorps

Épitope: AA 144-762

Fonction: Anti-TTLL3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TTLL3 Antibody Picoband® (ABIN7600063). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TTLL3 recombinant protein (Position: E144-R762).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bosch Grau, M., Gonzalez Curto, G., Rocha, C., Magiera, M. M., Marques Sousa, P., Giordano, T., Spassky, N., Janke, C. Tubulin glycylases and glutamylases have distinct functions in stabilization and motility of ependymal cilia. J. Cell Biol. 202: 441-451, 2013. 2. Bosch Grau, M., Masson, C., Gadadhar, S., Rocha, C., Tort, O., Marques Sousa, P., Vacher, S., Bieche, I., Janke, C. Alterations in the balance of tubulin glycylation and glutamylation in photoreceptors leads to retinal degeneration. J. Cell Sci. 130: 938-949, 2017. Note: Erratum: J. Cell Sci. 133: jcs244475, 2020. 3. Gadadhar, S., Alvarez Viar, G., Hansen, J. N., Gong, A., Kostarev, A., Ialy-Radio, C., Leboucher, S., Whitfield, M., Ziyyat, A., Toure, A., Alvarez, L., Pigino, G., Janke, C. Tubulin glycylation controls axonemal dynein activity, flagellar beat, and male fertility. Science 371: eabd4914, 2021.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TTLL3

Antigène: TTLL3 (Tubulin tyrosine Ligase-Like Family, Member 3 (TTLL3))

Autre désignation: TTLL3

Sujet:

Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24

Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Background: Tubulin tyrosine ligase-like family, member 3 is a protein that in humans is encoded by the TTLL3 gene. Enables protein-glycine ligase activity. Predicted to be involved in axoneme assembly and flagellated sperm motility. Predicted to be located in axoneme, microtubule cytoskeleton, and sperm flagellum.

Poids moléculaire: 87 kDa

ID gène: 26140

UniProt: Q9Y4R7