Cadherin 13 anticorps (AA 149-692)
Aperçu rapide pour Cadherin 13 anticorps (AA 149-692) (ABIN7600095)
Antigène
Voir toutes Cadherin 13 (CDH13) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 149-692
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Fonction
- Anti-H Cadherin/CDH13 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-H Cadherin/CDH13 Antibody (ABIN7600095). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human H Cadherin/CDH13 recombinant protein (Position: E149-A692).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Cadherin 13 (CDH13)
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Autre désignation
- CDH13
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Sujet
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Synonyms: Neuronal acetylcholine receptor subunit alpha-3, CHRNA3, NACHRA3
Background: T-cadherin also known as cadherin 13, H-cadherin (heart) (CDH13) is a unique member of cadherin superfamily because it lacks the transmembrane and cytoplasmic domains and is anchored to the cells membrane through the GPI anchor. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Poids moléculaire
- 105 kDa, 130 kDa
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ID gène
- 1012
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UniProt
- P55290
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Pathways
- EGFR Signaling Pathway, Cell-Cell Junction Organization
Antigène
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