TBR1 anticorps (AA 15-682)

N° du produit ABIN7600119

L’anticorps Lapin Polyclonal anti-TBR1 a été validé pour WB, ELISA, IHC et FACS. Il convient pour détecter TBR1 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TBR1 anticorps (AA 15-682) (ABIN7600119)

Antigène: TBR1 (T-Box Brain Gene 1 (TBR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-TBR1 anticorps

Épitope: AA 15-682

Fonction: Anti-TBR1 Antibody Picoband®

Attributs du produit: Anti-TBR1 Antibody Picoband® (ABIN7600119). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TBR1 recombinant protein (Position: K15-S682). Human TBR1 shares 99.3% amino acid (aa) sequence identity with mouse TBR1.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bulfone, A., Smiga, S. M., Shimamura, K., Peterson, A., Puelles, L., Rubenstein, J. L. R. T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron 15: 63-78, 1995. 2. den Hoed, J., Sollis, E., Venselaar, H., Estruch, S. B., Deriziotis, P., Fisher, S. E. Functional characterization of TBR1 variants in neurodevelopmental disorder. Sci. Rep. 8: 14279, 2018. 3. Deriziotis, P., O'Roak, B. J., Graham, S. A., Estruch, S. B., Dimitropoulou, D., Bernier, R. A., Gerdts, J., Shendure, J., Eichler, E. E., Fisher, S. E. De novo TBR1 mutations in sporadic autism disrupt protein functions. Nature Commun. 5: 4954, 2014. Note: Electronic Article.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TBR1

Antigène: TBR1 (T-Box Brain Gene 1 (TBR1))

Autre désignation: TBR1

Sujet: T-box, brain, 1 is a transcription factor protein important in vertebrate embryo development. It is encoded by the TBR1 gene. This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.

Poids moléculaire: 74 kDa

ID gène: 10716

UniProt: Q16650