SUOX anticorps (AA 163-434)

N° du produit ABIN7600212

Cet anticorps Lapin Polyclonal détecte spécifiquement SUOX dans WB, ELISA et FACS. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SUOX anticorps (AA 163-434) (ABIN7600212)

Antigène: SUOX (Sulfite Oxidase (SUOX))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUOX est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-SUOX anticorps

Épitope: AA 163-434

Fonction: Anti-Sulfite oxidase/SUOX Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Sulfite oxidase/SUOX Antibody Picoband® (ABIN7600212). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Sulfite oxidase/SUOX recombinant protein (Position: E163-D434).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bender, D., Kaczmarek, A. T., Santamaria-Araujo, J. A., Stueve, B., Waltz, S., Bartsch, D., Kurian, L., Cirak, S., Schwarz, G. Impaired mitochondrial maturation of sulfite oxidase in a patient with severe sulfite oxidase deficiency. Hum. Molec. Genet. 28: 2885-2899, 2019. 2. Garrett, R. M., Bellissimo, D. B., Rajagopalan, K. V. Molecular cloning of human liver sulfite oxidase. Biochim. Biophys. Acta 1262: 147-149, 1995. 3. Garrett, R. M., Johnson, J. L., Graf, T. N., Feigenbaum, A., Rajagopalan, K. V. Human sulfite oxidase R160Q: identification of the mutation in a sulfite oxidase-deficient patient and expression and characterization of the mutant enzyme. Proc. Nat. Acad. Sci. 95: 6394-6398, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SUOX

Antigène: SUOX (Sulfite Oxidase (SUOX))

Autre désignation: SUOX

Sujet:

Synonyms: T-lymphocyte surface antigen Ly-9, Cell surface molecule Ly-9, Lymphocyte antigen 9, SLAM family member 3, SLAMF3, Signaling lymphocytic activation molecule 3, CD229, LY9, CDABP0070

Tissue Specificity: Increased surface expression on T-cells of systemic lupus erythematosus (SLE) patients.

Background: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.

Poids moléculaire: 60 kDa

ID gène: 6821

UniProt: P51687