GBA3 anticorps (AA 17-469)
Aperçu rapide pour GBA3 anticorps (AA 17-469) (ABIN7600270)
Antigène
Voir toutes GBA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 17-469
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Fonction
- Anti-GBA3 Antibody Picoband®
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Attributs du produit
- Anti-GBA3 Antibody Picoband® (ABIN7600270). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human GBA3 recombinant protein (Position: Q17-L469).
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. de Graaf, M., van Veen, I. C., van der Meulen-Muileman, I. H., Gerritsen, W. R., Pinedo, H. M., Haisma, H. J. Cloning and characterization of human liver cytosolic beta-glycosidase. Biochem. J. 356: 907-910, 2001. 2. Hayashi, Y., Okino, N., Kakuta, Y., Shikanai, T., Tani, M., Narimatsu, H., Ito, M. Klotho-related protein is a novel cytosolic neutral beta-glycosylceramidase. J. Biol. Chem. 282: 30889-30900, 2007. 3. Yahata, K., Mori, K., Arai, H., Koide, S., Ogawa, Y., Mukoyama, M., Sugawara, A., Ozaki, S., Tanaka, I., Nabeshima, Y., Nakao, K. Molecular cloning and expression of a novel klotho-related protein. J. Molec. Med. 78: 389-394, 2000. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- GBA3 (Glucosidase, Beta, Acid 3 (Cytosolic) (GBA3))
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Autre désignation
- GBA3
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Sujet
- Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene. The protein encoded by this gene is a cytosolic enzyme that can hydrolyze several types of glycosides. The enzyme has its highest activity at neutral pH and is predominantly expressed in human liver, kidney, intestine, and spleen. This gene is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of this gene results in multiple transcript variants.
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Poids moléculaire
- 50 kDa
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ID gène
- 57733
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UniProt
- Q9H227
Antigène
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