Foxk1 anticorps (AA 175-671)

N° du produit ABIN7600295

Cet anticorps anti-Foxk1 est un anticorps Lapin Polyclonal détectant Foxk1 dans WB, ELISA, IHC, IF, FACS et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Foxk1 anticorps (AA 175-671) (ABIN7600295)

Antigène: Foxk1 (Forkhead Box K1 (Foxk1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Foxk1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-Foxk1 anticorps

Épitope: AA 175-671

Fonction: Anti-FOXK1/MNF Picoband® Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FOXK1/MNF Picoband® Antibody (ABIN7600295). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human FOXK1/MNF recombinant protein (Position: Q175-E671).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. awke, T. J., Jiang, N., Garry, D. J. Absence of p21(CIP) rescues myogenic progenitor cell proliferative and regenerative capacity in Foxk1 null mice. J. Biol. Chem. 278: 4015-4020, 2003. 2. Huang, J. T.-J., Lee, V. Identification and characterization of a novel human FOXK1 gene in silico. Int. J. Oncol. 25: 751-757, 2004. 3. Katoh, M., Katoh, M. Identification and characterization of human FOXK1 gene in silico. Int. J. Molec. Med. 14: 127-132, 2004.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Foxk1

Antigène: Foxk1 (Forkhead Box K1 (Foxk1))

Autre désignation: FOXK1

Sujet:

Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

Tissue Specificity: Expressed in kidney.

Background: Forkhead box protein K1 is a transcription factor of the forkhead box family that in humans is encoded by the FOXK1 gene. It is mapped to 7p22.1. FOXK1 is one of the transcription factors managing the passage from the normal cellular respiration (complete glucose oxidation) to generating ATP and intermediaries for many other biochemical pathways. FOXK1 and its closely relate sibling FOXK2 induce aerobic glycolysis by upregulating the enzymatic machinery required for this (for example, hexokinase-2, phosphofructokinase, pyruvate kinase, and lactate dehydrogenase), while at the same time suppressing further oxidation of pyruvate in the mitochondria by increasing the activity of pyruvate dehydrogenase kinases 1 and 4.

Poids moléculaire: 97 kDa

ID gène: 221937

UniProt: P85037