Synaptojanin 2 anticorps (AA 18-1495)

N° du produit ABIN7600318

L’anticorps Lapin Polyclonal anti-Synaptojanin 2 a été validé pour WB, ELISA et FACS. Il convient pour détecter Synaptojanin 2 dans des échantillons de Humain.

Aperçu rapide pour Synaptojanin 2 anticorps (AA 18-1495) (ABIN7600318)

Antigène: Synaptojanin 2 (SYNJ2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Synaptojanin 2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-Synaptojanin 2 anticorps

Épitope: AA 18-1495

Fonction: Anti-SYNJ2 Antibody Picoband®

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Anti-SYNJ2 Antibody Picoband® (ABIN7600300). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SYNJ2 recombinant protein (Position: D18-K1495). Human SYNJ2 shares 83.8% amino acid (aa) sequence identity with rat SYNJ2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chuang, Y., Tran, N. L., Rusk, N., Nakada, M., Berens, M. E., Symons, M. Role of synaptojanin 2 in glioma cell migration and invasion. Cancer Res. 64: 8271-8275, 2004. 2. Malecz, N., McCabe, P. C., Spaargaren, C., Qiu, R.-G., Chuang, Y., Symons, M. Synaptojanin 2, a novel Rac1 effector that regulates clathrin-mediated endocytosis. Curr. Biol. 10: 1383-1386, 2000. 3. Nagase, T., Ishikawa, K., Nakajima, D., Ohira, M., Seki, N., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 4: 141-150, 1997.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur Synaptojanin 2

Antigène: Synaptojanin 2 (SYNJ2)

Autre désignation: SYNJ2

Sujet:

Synonyms: 70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70 kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody

Tissue Specificity: Expressed in all tissues.

Background: Synaptojanin 2 is a protein that in humans is encoded by the SYNJ2 gene. The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 200 kDa

ID gène: 8871

UniProt: O15056

Pathways: Inositol Metabolic Process