SCFD2 anticorps (AA 20-585)

N° du produit ABIN7600557

Cet anticorps Lapin Polyclonal détecte spécifiquement SCFD2 dans WB, ELISA, ICC, FACS et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour SCFD2 anticorps (AA 20-585) (ABIN7600557)

Antigène: SCFD2 (Sec1 Family Domain Containing 2 (SCFD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCFD2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)

Détail du produit anti-SCFD2 anticorps

Épitope: AA 20-585

Fonction: Anti-SCFD2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SCFD2 Antibody Picoband® (ABIN7600557). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SCFD2 recombinant protein (Position: K20-H585).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mitobe, Y. , Iino, K. , Takayama, K. , Ikeda, K. , Suzuki, T. , & Aogi, K. , et al. (2020). Psf promotes er-positive breast cancer progression via posttranscriptional regulation of esr1 and scfd2. Cancer research, 80(11), 2230-2242. 2. Takeiwa, T. , Ikeda, K. , Suzuki, T. , Sato, W. , Iino, K. , & Mitobe, Y. , et al. (2022). Pspc1 is a potential prognostic marker for hormone-dependent breast cancer patients and modulates rna processing of esr1 and scfd2. Scientific reports, 12(1), 9495. 3. (2010). Genome-wide association identifies atoh7 as a major gene determining human optic disc size. Human Molecular Genetics, 19(13), 2716.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SCFD2

Antigène: SCFD2 (Sec1 Family Domain Containing 2 (SCFD2))

Autre désignation: SCFD2

Sujet:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: SCFD2 (sec1 family domain containing 2), also known as STXBP1L1 (syntaxinbinding protein 1-like 1), is a 684 amino acid protein suggested to play a role in protein transport. Existing as two alternatively spliced isoforms, SCFD2 is a member of the STXBP/unc-18/SEC1 family and is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease

Poids moléculaire: 75 kDa

ID gène: 152579