14-3-3 Pan (AA 174-245) anticorps
Aperçu rapide pour 14-3-3 Pan (AA 174-245) anticorps (ABIN726710)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 174-245
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Fonction
- 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon Antibody
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Sheep,Fruit Fly,yeast
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human 14-3-3
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Isotype
- IgG
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Indications d'application
- WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- 14-3-3 Pan
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Autre désignation
- 14-3-3 Alpha + Beta + Gamma + Delta + Epsilon
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Sujet
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Synonyms: HS1, GW128, YWHAA, KCIP-1, HEL-S-1, 14-3-3 protein beta/alpha, Protein 154, Protein kinase C inhibitor protein 1, YWHAB
Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.
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ID gène
- 7529
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UniProt
- P31946
Antigène
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