SMPD1 anticorps (AA 204-558)

N° du produit ABIN7600575

Cet anticorps Lapin Polyclonal détecte spécifiquement SMPD1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Souris et Rat.

Aperçu rapide pour SMPD1 anticorps (AA 204-558) (ABIN7600575)

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMPD1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SMPD1 anticorps

Épitope: AA 204-558

Fonction: Anti-Smpd1 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Smpd1 Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Smpd1 recombinant protein (Position: D204-M558).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SMPD1

Antigène: SMPD1 (Sphingomyelin phosphodiesterase 1, Acid Lysosomal (SMPD1))

Autre désignation: Smpd1

Sujet:

Background: Sphingomyelin phosphodiesterase 1 (SMPD1), also known as acid sphingomyelinase (ASM), is an enzyme that in humans is encoded by the SMPD1 gene. Enables acid sphingomyelin phosphodiesterase activity and zinc ion binding activity. Involved in ceramide biosynthetic process, positive regulation of apoptotic process, and response to ionizing radiation. Acts upstream of or within ceramide metabolic process, cholesterol metabolic process, and sphingomyelin catabolic process. Located in extracellular space. Is expressed in several structures, including alimentary system, integumental system, nervous system, sensory organ, and skeleton. Used to study Niemann-Pick disease. Human ortholog(s) of this gene implicated in Niemann-Pick disease, Niemann-Pick disease type A, and Niemann-Pick disease type B. Orthologous to human SMPD1 (sphingomyelin phosphodiesterase 1).

Gene Full Name: sphingomyelin phosphodiesterase 1, acid lysosomal

Poids moléculaire: 70 kDa

ID gène: 20597

UniProt: Q04519