SCYL2 anticorps (AA 208-909)

N° du produit ABIN7600588

L’anticorps Lapin Polyclonal anti-SCYL2 a été validé pour WB, ELISA, IF, FACS et ICC. Il convient pour détecter SCYL2 dans des échantillons de Humain.

Aperçu rapide pour SCYL2 anticorps (AA 208-909) (ABIN7600588)

Antigène: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCYL2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-SCYL2 anticorps

Épitope: AA 208-909

Fonction: Anti-SCYL2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-SCYL2 Antibody Picoband® (ABIN7600588). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SCYL2 recombinant protein (Position: E208-Q909).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Conner, S. D., Schmid, S. L. CVAK104 is a novel poly(L)-lysine-stimulated kinase that targets the beta-2-subunit of AP2. J. Biol. Chem. 280: 21539-21544, 2005. 2. Gingras, S., Earls, L. R., Howell, S., Smeyne, R. J., Zakharenko, S. S., Pelletier, S. SCYL2 protects CA3 pyramidal neurons from excitotoxicity during functional maturation of the mouse hippocampus. J. Neurosci. 35: 10510-10522, 2015. 3. Gross, M. B. Personal Communication. Baltimore, Md. 5/15/2015.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SCYL2

Antigène: SCYL2 (SCY1-Like 2 (SCYL2))

Autre désignation: SCYL2

Sujet:

Synonyms: Gap junction gamma-1 protein,Connexin-45,Cx45,Gap junction alpha-7 protein,GJC1,GJA7,

Tissue Specificity: Ubiquitously expressed.

Background: SCY1-like protein 2 is a protein that in humans is encoded by the SCYL2 gene. The protein encoded by this gene associates with clathrin-coated complexes at the plasma membrane and with endocytic coated vesicles. The encoded protein phosphorylates the beta2 subunit of the plasma membrane adapter complex AP2 and interacts with clathrin, showing involvement in clathrin-dependent pathways between the trans-Golgi network and the endosomal system. In addition, this protein has a role in the Wnt signaling pathway by targeting frizzled 5 (Fzd5) for lysosomal degradation. Two transcript variants encoding the same protein have been found for this gene.

Poids moléculaire: 104 kDa

ID gène: 55681

UniProt: Q6P3W7