GMP Synthase anticorps (AA 21-671)

N° du produit ABIN7600629

Cet anticorps Lapin Polyclonal détecte spécifiquement GMP Synthase dans WB, ELISA et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GMP Synthase anticorps (AA 21-671) (ABIN7600629)

Antigène: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GMP Synthase est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-GMP Synthase anticorps

Épitope: AA 21-671

Fonction: Anti-GMPS Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-GMPS Antibody Picoband® (ABIN7600629). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GMPS recombinant protein (Position: H21-K671).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hirst, M., Haliday, E., Nakamura, J., Lou, L. Human GMP synthetase: protein purification, cloning, and functional expression of cDNA. J. Biol. Chem. 269: 23830-23837, 1994. 2. Pegram, L. D., Megonigal, M. D., Lange, B. J., Nowell, P. C., Rowley, J. D., Rappaport, E. F., Felix, C. A. t(3,11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (guanosine 5-prime monophosphate synthetase) gene. Blood 96: 4360-4362, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur GMP Synthase

Antigène: GMP Synthase (GMPS) (Guanine Monophosphate Synthetase (GMPS))

Autre désignation: GMPS

Sujet:

Synonyms: DNA replication licensing factor MCM5, CDC46 homolog, P1-CDC46, MCM5, CDC46

Tissue Specificity: Ubiquitous.

Background: Guanosine monophosphate synthetase, also known as GMPS is an enzyme that converts xanthosine monophosphate to guanosine monophosphate. In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.

Poids moléculaire: 77 kDa

ID gène: 8833

UniProt: P49915

Pathways: Ribonucleoside Biosynthetic Process