OAT anticorps (AA 214-439)

N° du produit ABIN7600649

Cet anticorps anti-OAT est un anticorps Lapin Polyclonal détectant OAT dans WB, ELISA, IHC et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour OAT anticorps (AA 214-439) (ABIN7600649)

Antigène: OAT (Ornithine Aminotransferase (OAT))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OAT est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-OAT anticorps

Épitope: AA 214-439

Fonction: Anti-ornithine aminotransferase/OAT Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ornithine aminotransferase/OAT Antibody Picoband® (ABIN7600649). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OAT recombinant protein (Position: A214-F439).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Akaki, Y., Hotta, Y., Mashima, Y., Murakami, A., Kennaway, N. G., Weleber, R. G., Inana, G. A deletion in the ornithine aminotransferase gene in gyrate atrophy. J. Biol. Chem. 267: 12950-12954, 1992. 2. Barrett, D. J., Bateman, J. B., Sparkes, R. S., Mohandas, T., Klisak, I., Inana, G. Chromosomal localization of human ornithine aminotransferase gene sequences to 10q26 and Xp11.2. Invest. Ophthal. Vis. Sci. 28: 1037-1042, 1987. 3. Bisaillon, J. J., Radden, L. A., II, Szabo, E. T., Hughes, S. R., Feliciano, A. M., Nesta, A. V., Petrovic, B., Palanza, K. M., Lancinskas, D., Szmurlo, T. A., Artus, D. C., Kapper, M. A., Mulrooney, J. P., King, T. R. The retarded hair growth (rhg) mutation in mice is an allele of ornithine aminotransferase (Oat). Molec. Genet. Metab. Rep. 1: 378-390, 2014.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur OAT

Antigène: OAT (Ornithine Aminotransferase (OAT))

Autre désignation: OAT

Sujet:

Synonyms: Podoplanin, Aggrus, Glycoprotein 36, Gp36, PA2.26 antigen, T1-alpha, T1A, 29 kDa cytosolic podoplanin intracellular domain, PICD, PDPN, GP36, PSEC0003, PSEC0025

Tissue Specificity: Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium. Up-regulated in colorectal tumors and expressed in 25 % of early oral squamous cell carcinomas.

Background: Ornithine aminotransferase (OAT) is an enzyme which is encoded in human by the OAT gene located on chromosome 10. This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

Poids moléculaire: 49 kDa

ID gène: 4942

UniProt: P04181