RAB23 anticorps (AA 22-168)

N° du produit ABIN7600675

L’anticorps Lapin Polyclonal anti-RAB23 a été validé pour WB, ELISA et FACS. Il convient pour détecter RAB23 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RAB23 anticorps (AA 22-168) (ABIN7600675)

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB23 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RAB23 anticorps

Épitope: AA 22-168

Fonction: Anti-RAB23 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-RAB23 Antibody Picoband® (ABIN7600675). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RAB23 recombinant protein (Position: K22-K168).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alessandri, J.-L., Dagoneau, N., Laville, J.-M., Baruteau, J., Hebert, J.-C., Cormier-Daire, V. RAB23 mutation in a large family from Comoros Islands with Carpenter syndrome. Am. J. Med. Genet. 152A: 982-986, 2010. 2. Eggenschwiler, J. T., Espinoza, E., Anderson, K. V. Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature 412: 194-198, 2001. 3. Gunther, T., Struwe, M., Aguzzi, A., Schughart, K. open brain, a new mouse mutant with severe neural tube defects, shows altered gene expression patterns in the developing spinal cord. Development 120: 3119-3130, 1994.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur RAB23

Antigène: RAB23 (RAB23, Member RAS Oncogene Family (RAB23))

Autre désignation: RAB23

Sujet:

Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2

Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.

Background: Ras-related protein Rab-23 is a protein that in humans is encoded by the RAB23 gene. This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 27 kDa

ID gène: 51715

Pathways: Tube Formation