PTH2R anticorps (AA 22-511)

N° du produit ABIN7600696

L’anticorps Lapin Polyclonal anti-PTH2R a été validé pour WB, ELISA, ICC et IF. Il convient pour détecter PTH2R dans des échantillons de Humain.

Aperçu rapide pour PTH2R anticorps (AA 22-511) (ABIN7600696)

Antigène: PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTH2R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-PTH2R anticorps

Épitope: AA 22-511

Fonction: Anti-PTH2R Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PTH2R Antibody Picoband® (ABIN7600696). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PTH2R recombinant protein (Position: A22-E511).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clark, J. A., Bonner, T. I., Kim, A. S., Usdin, T. B. Multiple regions of ligand discrimination revealed by analysis of chimeric parathyroid hormone 2 (PTH2) and PTH/PTH-related peptide (PTHrP) receptors. Molec. Endocr. 12: 193-206, 1998. 2. Kim, J., Won, H.-H., Kim, Y., Choi, J. R., Yu, N., Lee, K.-A. Breakpoint mapping by whole genome sequencing identifies PTH2R gene disruption in a patient with midline craniosynostosis and a de novo balanced chromosomal rearrangement. J. Med. Genet. 52: 706-709, 2015. 3. Meulenbelt, I., Min, J. L., van Duijn, C. M., Kloppenburg, M., Breedveld, F. C., Slagboom, P. E. Strong linkage on 2q33.3 to familial early-onset generalized osteoarthritis and a consideration of two positional candidate genes. Europ. J. Hum. Genet. 14: 1280-1287, 2006.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PTH2R

Antigène: PTH2R (Parathyroid Hormone 2 Receptor (PTH2R))

Autre désignation: PTH2R

Sujet:

Synonyms: Pre T-cell antigen receptor alpha, pT-alpha, pTa, pT-alpha-TCR, PTCRA

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Parathyroid hormone 2 receptor is a protein that in humans is encoded by the PTH2R gene. The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 75 kDa

ID gène: 5746

UniProt: P49190

Pathways: cAMP Metabolic Process