PPFIA2 anticorps (AA 221-1257)

N° du produit ABIN7600706

Cet anticorps anti-PPFIA2 est un anticorps Lapin Polyclonal détectant PPFIA2 dans WB, ELISA, FACS et IHC. Adapté pour Souris, Humain et Rat.

Aperçu rapide pour PPFIA2 anticorps (AA 221-1257) (ABIN7600706)

Antigène: PPFIA2 (Protein Tyrosine Phosphatase F Interacting Protein 2 (PPFIA2))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPFIA2 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Détail du produit anti-PPFIA2 anticorps

Épitope: AA 221-1257

Fonction: Anti-PPFIA2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PPFIA2 Antibody Picoband® (ABIN7600706). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PPFIA2 recombinant protein (Position: E221-C1257).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 9/2/2022. 2. Serra-Pages, C., Medley, Q. G., Tang, M., Hart, A., Streuli, M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273: 15611-15620, 1998. 3. Stucchi, R., Plucinska, G., Hummel, J. J. A., Zahavi, E. E., Guerra San Juan, I., Klykov, O., Scheltema, R. A., Maarten Altelaar, A. F., Hoogenraad, C. C. Regulation of KIF1A-driven dense core vesicle transport: Ca(2+)/CaM controls DCV binding and liprin-alpha/TANC2 recruits DCVs to postsynaptic sites. Cell Rep. 24: 685-700, 2018.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PPFIA2

Antigène: PPFIA2 (Protein Tyrosine Phosphatase F Interacting Protein 2 (PPFIA2))

Autre désignation: PPFIA2

Sujet:

Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24

Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.

Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants

Poids moléculaire: 143 kDa

ID gène: 8499

UniProt: O75334