Cytokeratin 1 anticorps (AA 223-439)
Aperçu rapide pour Cytokeratin 1 anticorps (AA 223-439) (ABIN7600713)
Antigène
Voir toutes Cytokeratin 1 (KRT1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 223-439
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Fonction
- Anti-Cytokeratin 1/Krt1 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Cytokeratin 1/Krt1 Antibody. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Mouse.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived mouse Cytokeratin 1/Krt1 recombinant protein (Position: L223-Q439).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse Immunofluorescence, 5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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Autre désignation
- Krt1
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Sujet
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Background: Keratin 1 (KRT1), also known as Cytokeratin 1, or Keratin, type II cytoskeletal 1, is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants ofbullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. And this type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Gene Full Name: keratin 1
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Poids moléculaire
- 66 kDa
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ID gène
- 16678
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UniProt
- P04104
Antigène
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