PRTN3 anticorps (AA 23-241)
Aperçu rapide pour PRTN3 anticorps (AA 23-241) (ABIN7600742)
Antigène
Voir toutes PRTN3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 23-241
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Fonction
- Anti-PRTN3 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-PRTN3 Antibody Picoband® (ABIN7600742). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PRTN3 recombinant protein (Position: A23-D241).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Belaaouaj, A., Walsh, B. C., Jenkins, N. A., Copeland, N. G., Shapiro, S. D. Characterization of the mouse neutrophil elastase gene and localization to chromosome 10. Mammalian Genome 8: 5-8, 1997. 2. Campanelli, D., Melchior, M., Fu, Y., Nakata, M., Shuman, H., Nathan, C., Gabay, J. E. Cloning of cDNA for proteinase 3: a serine protease, antibiotic, and autoantigen from human neutrophils. J. Exp. Med. 172: 1709-1715, 1990. 3. Davies, D. J., Moran, J. E., Niall, J. F., Ryan, G. B. Segmental necrotising glomerulonephritis with antineutrophil antibody: possible arbovirus aetiology. Brit. Med. J. 285: 606 only, 1982. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- PRTN3 (Proteinase 3 (PRTN3))
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Autre désignation
- PRTN3
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Sujet
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Synonyms: AF4/FMR2 family member 4,ALL1-fused gene from chromosome 5q31 protein,Protein AF-5q31,Major CDK9 elongation factor-associated protein,AFF4,AF5Q31, MCEF,HSPC092,
Tissue Specificity: Ubiquitously expressed. Strongly expressed in heart, placenta, skeletal muscle, pancreas and to a lower extent in brain. .
Background: Proteinase 3, also known as PRTN3, is an enzyme that in humans is encoded by the PRTN3 gene. Enables enzyme binding activity, serine-type endopeptidase activity, and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation, membrane protein ectodomain proteolysis, and neutrophil extravasation. Located in azurophil granule lumen, cytosol, and plasma membrane raft. Colocalizes with plasma membrane.
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Poids moléculaire
- 32 kDa
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ID gène
- 5657
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UniProt
- P24158
Antigène
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