RALBP1 anticorps (AA 239-506)

N° du produit ABIN7600799

Cet anticorps anti-RALBP1 est un anticorps Souris Monoclonal détectant RALBP1 dans WB et FACS. Adapté pour Humain.

Aperçu rapide pour RALBP1 anticorps (AA 239-506) (ABIN7600799)

Antigène: RALBP1 (RalA Binding Protein 1 (RALBP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RALBP1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 2E11

Détail du produit anti-RALBP1 anticorps

Épitope: AA 239-506

Fonction: Anti-RALBP1 Antibody Picoband® (monoclonal, 2E11)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-RALBP1 Antibody Picoband® (monoclonal, 2E11) (ABIN7600799). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human RALBP1 recombinant protein (Position: K239-Q506).

Isotype: IgG2a

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. "Entrez Gene: RALBP1 ralA binding protein 1". 2. Kashatus, D. F., Lim, K.-H., Brady, D. C., Pershing, N. L. K., Cox, A. D., Counter, C. M. RALA and RALBP1 regulate mitochondrial fission at mitosis. Nature Cell Biol. 13: 1108-1115, 2011.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur RALBP1

Antigène: RALBP1 (RalA Binding Protein 1 (RALBP1))

Autre désignation: RALBP1

Sujet:

Synonyms: B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, CD79B, B29, IGB

Tissue Specificity: Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Background: RalA-binding protein 1 is a protein that in humans is encoded by the RALBP1 gene. Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS, which in turn is activated by RAS. RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL. RALBP1 is also the dominant transporter of lipid peroxidation-derived glutathione conjugates and participates in several mitotic events, including inactivation of endocytosis and separation and polar movement of centrioles and appropriate distribution of mitochondria to daughter cells following mitosis.

Poids moléculaire: 95 kDa

ID gène: 10928

UniProt: Q15311