Desmoglein 2 anticorps (AA 24-1020)
Aperçu rapide pour Desmoglein 2 anticorps (AA 24-1020) (ABIN7600803)
Antigène
Voir toutes Desmoglein 2 (DSG2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-1020
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Fonction
- Anti-Desmoglein 2/DSG2 Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Desmoglein 2/DSG2 Antibody. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Desmoglein 2/DSG2 recombinant protein (Position: L24-E1020).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Desmoglein 2 (DSG2)
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Autre désignation
- DSG2
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Sujet
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Background: Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance.
Gene Full Name: desmoglein 2
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Poids moléculaire
- 160 kDa
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ID gène
- 1829
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UniProt
- Q14126
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Pathways
- Cell-Cell Junction Organization
Antigène
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