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DCT anticorps (AA 24-519)

L’anticorps Lapin Polyclonal anti-DCT a été validé pour WB, ELISA et FACS. Il convient pour détecter DCT dans des échantillons de Humain, Souris et Rat.
N° du produit ABIN7600843

Aperçu rapide pour DCT anticorps (AA 24-519) (ABIN7600843)

Antigène

Voir toutes DCT Anticorps
DCT (Dopachrome Tautomerase (DCT))

Reactivité

  • 67
  • 22
  • 7
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 65
  • 2
Lapin

Clonalité

  • 65
  • 2
Polyclonal

Conjugué

  • 40
  • 6
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp DCT est non-conjugé

Application

  • 55
  • 36
  • 21
  • 7
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Épitope

    • 17
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-519

    Fonction

    Anti-TRP2/DCT Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-TRP2/DCT Antibody Picoband® (ABIN7600843). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human TRP2/DCT recombinant protein (Position: Q24-A519).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bouchard, B., Del Marmol, V., Jackson, I. J., Cherif, D., Dubertret, L. Molecular characterization of a human tyrosinase-related-protein-2 cDNA: patterns of expression in melanocytic cells. Europ. J. Biochem. 219: 127-134, 1994. 2. Budd, P. S., Jackson, I. J. Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles. Genomics 29: 35-43, 1995. 3. Cassady, J. L., Sturm, R. A. Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA. Gene 143: 295-298, 1994.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    DCT (Dopachrome Tautomerase (DCT))

    Autre désignation

    DCT

    Sujet

    Synonyms: Beta-galactosidase, Glb1, Glb1_mapped, rCG_25043

    Background: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

    Poids moléculaire

    59 kDa

    ID gène

    1638

    UniProt

    P40126
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