FGF15 anticorps (AA 26-218)

N° du produit ABIN7600946

Cet anticorps anti-FGF15 est un anticorps Lapin Polyclonal détectant FGF15 dans IHC. Adapté pour Rat et Souris.

Aperçu rapide pour FGF15 anticorps (AA 26-218) (ABIN7600946)

Antigène: FGF15 (Fibroblast Growth Factor 15 (FGF15))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FGF15 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FGF15 anticorps

Épitope: AA 26-218

Fonction: Anti-Fgf19(Fgf15) Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Fgf19(Fgf15) Antibody Picoband® (ABIN7600946). Tested in IHC applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived rat Fgf19(Fgf15) recombinant protein (Position: R26-K218). Rat Fgf19(Fgf15) shares 53.2% and 96.4% amino acid (aa) sequence identity with human and mouse FGF19, respectively.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
1. Jones, SA (2012). "Physiology of FGF15/19". Advances in Experimental Medicine and Biology. 728: 171-82. 2. Potthoff, MJ, Kliewer, SA, Mangelsdorf, DJ (2012). "Endocrine fibroblast growth factors 15/19 and 21: from feast to famine". Genes & Development. 26 (4): 312-324. 3. Owen, BM, Mangelsdorf, DJ, Kliewer, SA (January 2015). "Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21". Trends in Endocrinology and Metabolism. 26 (1): 22-9.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur FGF15

Antigène: FGF15 (Fibroblast Growth Factor 15 (FGF15))

Autre désignation: Fgf19(Fgf15)

Sujet:

Synonyms: Fibroblast growth factor 19,FGF-19,FGF19,UNQ334/PRO533,

Tissue Specificity: Expressed in fetal brain, cartilage, retina, and adult gall bladder. .

Background: FGF15/19 refers to two orthologous fibroblast growth factors which share 50 % aminoacid identity and have similar functions. FGF15 was described in the mouse, FGF19 was found in humans and other species. They share physiological functions and so are often referred to as FGF15/19 or as FGF15/FGF19. They were first described in developing fetal brain. They are now known to be produced in the ileum, and under certain circumstances in the liver and biliary tree. It is thought their principal function is in response to bile acid absorption occurring after meals. FGF15 and FGF19 have similar roles in regulating bile acid synthesis and also glucose metabolism in the liver.

Poids moléculaire: 24 kDa

ID gène: 170582, 14170