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PDLIM7 anticorps (AA 275-457)

Cet anticorps anti-PDLIM7 est un anticorps Lapin Polyclonal détectant PDLIM7 dans WB, ELISA, IHC et FACS. Adapté pour Humain, Souris et Rat.
N° du produit ABIN7601048

Aperçu rapide pour PDLIM7 anticorps (AA 275-457) (ABIN7601048)

Antigène

Voir toutes PDLIM7 Anticorps
PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Reactivité

  • 26
  • 6
  • 6
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 22
  • 4
Lapin

Clonalité

  • 23
  • 3
Polyclonal

Conjugué

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PDLIM7 est non-conjugé

Application

  • 17
  • 6
  • 6
  • 6
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Épitope

    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 275-457

    Fonction

    Anti-PDLIM7 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-PDLIM7 Antibody Picoband® (ABIN7601048). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human PDLIM7 recombinant protein (Position: N275-V457).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bach, I. The LIM domain: regulation by association. Mech. Dev. 91: 5-17, 2000. 2. Durick, K., Gill, G. N., Taylor, S. S. Shc and Enigma are both required for mitogenic signaling by Ret/ptc2. Molec. Cell. Biol. 18: 2298-2308, 1998. 3. Guy, P. M., Kenny, D. A., Gill, G. N. The PDZ domain of the LIM protein enigma binds to beta-tropomyosin. Molec. Biol. Cell 10: 1973-1984, 1999.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

    Autre désignation

    PDLIM7

    Sujet

    Synonyms: "Long-chain-fatty-acid--CoA ligase 4, Long-chain acyl-CoA synthetase 4, LACS 4, ACSL4, ACS4, FACL4, LACS4 "

    Tissue Specificity: Expressed in the prostate gland and prostate cancers.

    Background: PDZ and LIM domain protein 7 is a protein that in humans is encoded by the PDLIM7 gene. The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

    Poids moléculaire

    50 kDa

    ID gène

    9260
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