ICAM1 anticorps (AA 28-268)

N° du produit ABIN7601066

Cet anticorps anti-ICAM1 est un anticorps Souris Monoclonal détectant ICAM1 dans WB, FACS et IHC. Adapté pour Humain.

Aperçu rapide pour ICAM1 anticorps (AA 28-268) (ABIN7601066)

Antigène: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 6F2C3

Détail du produit anti-ICAM1 anticorps

Épitope: AA 28-268

Fonction: Anti-ICAM1 Antibody Picoband® (monoclonal, 6F2C3)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ICAM1 Antibody Picoband® (monoclonal, 6F2C3) (ABIN7601066). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ICAM1 recombinant protein (Position: Q28-R268).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Ballantyne, C. M., Kozak, C. A., O'Brien, W. E., Beaudet, A. L. : Assignment of the gene for intercellular adhesion molecule-1 (Icam-1) to proximal mouse chromosome 9. Genomics 9: 547-550, 1991. 2. Greve, J. M., Davis, G., Meyer, A. M., Forte, C. P., Yost, S. C., Marlor, C. W., Kamarck, M. E., McClelland, A. : The major human rhinovirus receptor is ICAM-1. Cell 56: 839-847, 1989. 3. Prieto, J., Takei, F., Gendelman, R., Christenson, B., Biberfeld, P., Patarroyo, M. : MALA-2, mouse homologue of human adhesion molecule ICAM-1 (CD54). Europ. J. Immun. 19: 1551-1557, 1989.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ICAM1

Antigène: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Autre désignation: ICAM1

Sujet:

Synonyms: Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1

Tissue Specificity: Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues.

Background: CD54, also known as ICAM-1. Intercellular adhesion molecule-1 (ICAM1) is a ligand for lymphocyte function-associated (LFA) antigens. ICAM-1 is an integral membrane protein, a member of the immunoglobulin superfamily, and a ligand for LFA-1, a beta 2 leukocyte integrin. This protein is the major human rhinovirus receptor. The ICAM1 gene is mapped to human chromosome 19. In humans, lymphocyte adhesion to cells is mediated by the protein heterodimer CD11a/CD18 (Leu-CAMa, LFA-1) and its ligand CD54 (ICAM-1).

Poids moléculaire: 90-110 kDa

ID gène: 3383

UniProt: P05362

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling