TOE1 anticorps (AA 28-501)

N° du produit ABIN7601080

L’anticorps Lapin Polyclonal anti-TOE1 a été validé pour WB, ELISA, IF, ICC et FACS. Il convient pour détecter TOE1 dans des échantillons de Humain.

Aperçu rapide pour TOE1 anticorps (AA 28-501) (ABIN7601080)

Antigène: TOE1 (Target of EGR1, Member 1 (Nuclear) (TOE1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOE1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-TOE1 anticorps

Épitope: AA 28-501

Fonction: Anti-TOE1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TOE1 Antibody Picoband® (ABIN7601080). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TOE1 recombinant protein (Position: E28-Q501).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anderson, C., Davies, J. H., Lamont, L., Foulds, N. Early pontocerebellar hypoplasia with vanishing testes: a new syndrome? Am. J. Med. Genet. 155A: 667-672, 2011. 2. Brault, L. S., Cooper, C. A., Famula, T. R., Murray, J. D., Penedo, M. C. T. Mapping of equine cerebellar abiotrophy to ECA2 and identification of a potential causative mutation affecting expression of MUTYH. Genomics 97: 121-129, 2011. 3. de Belle, I., Wu, J.-X., Sperandio, S., Mercola, D., Adamson, E. D. In vivo cloning and characterization of a new growth suppressor protein TOE1 as a target gene of Egr1. J. Biol. Chem. 278: 14306-14312, 2003.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TOE1

Antigène: TOE1 (Target of EGR1, Member 1 (Nuclear) (TOE1))

Autre désignation: TOE1

Sujet:

Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

Background: Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene. Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7.

Poids moléculaire: 57 kDa

ID gène: 114034